High Throughput Recombinant Antibody Production

cusabio specializes in the production of antibody

With 13+ years experience of antibody production, CUSABIO has developed and produced tens of thousands of quality antibodies for life science research. Currently, CUSABIO has established the HTP (high throughput) platform for recombinant antibody production, we specialized in antibody drug research and development that only provide services rather than drugs.

CUSABIO aims to offer rapid production service of recombinant antibodies to pharmaceutical companies, and enables them to pick out the “right” therapeutic antibodies in a short time with very competitive quotation.

Reference

CUSABIO is a leading biotechnology company specialized in production of high quality products for gene, protein, antibody, ELISA kit. Our products have been widely used by researchers in the worldwide. Now, we have listed a part of the publications citing our products, you can enter the catalog number to search the products what you want and see the corresponding reference.

Custom Recombinant Antibody Production

Recombinant antibody, also known as genetic engineering antibody, refers to the usage of recombinant DNA and protein engineering technology to modify or recombine antibody genes according to various needs, then expressed after transfection via appropriate receptor cell.
Cusabio could offer one-stop service of recombinant antibody production to customers upon your various needs.
The production process of Cusabio custom recombinant antibody is as follows.

cusabio specializes in the production of antibody
cusabio specializes in the production of antibody

Process & Deliverables:

Antigen Preparation Process Deliverables Production Time
Peptide Synthesis
  • Select Positive Gene
  • Recombinant Antibody Expression
  • Protein A/G Purification
  • ELISA, WB Validation
  1. QC report of antigen;
  2. 100ug×purified recombinant antibodies together with QC report, including the information of gene sequencing, concentration, purity and endotoxin content;
  3. WB positive guarantee for antigen;
  4. Other applications(IHC, IF, IP, FC, ChIP) could be available upon customers’ requests.
8-16 weeks
Recombinant Protein Production 12-16 weeks
Native Protein Selection 12-16 weeks

B cell

B cells, also known as B lymphocytes, are a type of white blood cell of the small lymphocyte subtype. Mature B cells mainly reside in the lymph nodes in the superficial layer of the lymph node cortex and in the red and white nodes of the spleen. B cells can differentiate into plasma cells under the stimulation of antigens. Plasma cells can synthesize and secrete antibodies (immunoglobulins), mainly performing humoral immunity of the body. In this article, we collect several question about B cell, and want to these information help you understand this kind of cell.

What is The Function of B Cell?

The function of B cell mainly includes two sections. On the one hand, they function in the humoral immunity component of the adaptive immune system by secreting antibodies. These antibodies serve as flags or the flares over a battle site. They recruit other defensive molecules in the bloodstream to the site, working toward killing the infection-causing organism. They also signal other immune cells to, in turn, wage war on the invader.

In addition to their essential role in humoral immunity, B cells also regulate many other functions essential for immune homeostasis. Of major importance, B cells are required for the initiation of T-cell immune responses by B cells antigen presenting and cytokines secreting. In mammals, B cells mature in the bone marrow, which is at the core of most bones. In birds, B cells mature in the bursa of Fabricius, a lymphoid organ where they were first discovered by Chang and Glick, and not from bone marrow as commonly believed.

What is The B Cell Differentiation?

The differentiation process of mammalian B cells can be divided into five stages: pre-B cells, immature B cells, mature B cells, activated B cells, and plasma cells. Among them, the differentiation of pre-B cells and immature B cells is antigen-untrusted, and the differentiation process is performed in the bone marrow. The antigen-dependent phase refers to mature B cells that are activated after antigen stimulation and continue to differentiate into plasma cells that synthesize and secrete antibodies. This stage of differentiation is mainly performed in peripheral immune organs.

Some of the activated B-cells become memory B-cells, which have very long lives in the bone marrow, lymph nodes and spleen. They remember the antigen they are specific for and are ready to respond quickly if they see it again. These are the cells that give us long-lasting immunity to different invaders. (Figure 1).

 

YB1 recombinant monoclonal antibody

A5510 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human YB1 for WB, IHC, IF,ELISA

Id1 recombinant monoclonal antibody

A5540 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human Id1 for WB, IHC, IF,ELISA

Fyn recombinant monoclonal antibody

A5547 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human Fyn for WB ,ELISA

TTR recombinant monoclonal antibody

A5560 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human TTR for WB, IHC,ELISA

MIF recombinant monoclonal antibody

A5561 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human MIF for WB ,ELISA

FTO recombinant monoclonal antibody

A5594 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human FTO for WB ,ELISA

p63 recombinant monoclonal antibody

A5182 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human p63 for WB, IHC, IF,ELISA

GFP recombinant monoclonal antibody

A5221 100ul X 3
EUR 817.2
Description: A recombinant monoclonal antibody from rabbit against human GFP for WB,ELISA

ERG recombinant monoclonal antibody

A5252 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human ERG for WB, IHC, IF,ELISA

AIF recombinant monoclonal antibody

A5256 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human AIF for WB, IHC, IF,ELISA

5T4 recombinant monoclonal antibody

A5271 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human 5T4 for WB, IHC,ELISA

p73 recombinant monoclonal antibody

A5272 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human p73 for WB, IHC,ELISA

Bid recombinant monoclonal antibody

A5293 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human Bid for WB, IHC,ELISA

PKR recombinant monoclonal antibody

A5330 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human PKR for WB,ELISA

IDE recombinant monoclonal antibody

A5386 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human IDE for WB,ELISA

p23 recombinant monoclonal antibody

A5407 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human p23 for WB, IHC,ELISA

PDI recombinant monoclonal antibody

A5449 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human PDI for WB,ELISA

Src recombinant monoclonal antibody

A5066 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human Src for WB, IHC, IF,ELISA

CD4 recombinant monoclonal antibody

A5067 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human CD4 for WB,ELISA

Bak recombinant monoclonal antibody

A5068 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human Bak for WB, IHC,ELISA

EGF recombinant monoclonal antibody

A5094 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human EGF for WB,ELISA

CD9 recombinant monoclonal antibody

A5099 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human CD9 for WB, IF,ELISA

CD8 recombinant monoclonal antibody

A5113 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human CD8 for WB,ELISA

Bim recombinant monoclonal antibody

A5114 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human Bim for WB, IHC,ELISA

Bax recombinant monoclonal antibody

A5131 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human Bax for WB, IHC, IF,ELISA

SP1 recombinant monoclonal antibody

A5138 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human SP1 for WB, IHC, IF,ELISA

Bad recombinant monoclonal antibody

A5147 100ul X 3
EUR 714
Description: A recombinant monoclonal antibody from rabbit against human Bad for WB, IHC,ELISA