kashbiotech

Monoclonal and Bispecific Anti-BCMA Antibodies in A number of Myeloma

 

  • B-cell maturation antigen (BCMA), a member of the tumor necrosis situation receptor superfamily, is universally expressed by common and neoplastic plasma cells and performs a important operate inside the proliferation, survival and tumor improvement in various myeloma(MM). B-cell activating situation (BAFF) and a proliferation-inducing ligand (APRIL) have been acknowledged as proliferation ligands for BCMA inside the bone marrow microenvironment.

 

  • Soluble BCMA ranges inside the serum correlates with sickness part and tumor burden and is a predictor of progression-free survival (PFS) and normal survival (OS). Not too way back, the introduction of new monoclonal antibodies in opposition to CD38 (Daratumumab and Isatuximab) and SLAM7 (Elotuzumab) has modified the therapeutic methodology to MM, bettering the response payment and the time to improvement, every in newly acknowledged and refractory/relapsed victims.

 

  • Among the many many flooring antigens on MM cells, BCMA is a suitable objective for the design of newest antibody-based strategies. Experimental approaches specializing in BCMA are for the time being being investigated and embrace antibody-drug conjugates (ADCs), bispecific antibodies (bsAbs) and genetically engineered T-cells with chimeric antigen receptors (CAR).

 

  • On this evaluation we summarize the newer findings about BCMA biologic rationale as a therapeutic objective and report the updated outcomes of preclinical and scientific analysis focused on ADCs and bsAbs specializing in BCMA.
kashbiotech
kashbiotech

Characterization of Variable Space Genes and Discovery of Key Recognition Web sites inside the Complementarity Determining Areas of the Anti-Thiacloprid Monoclonal Antibody

  • Sequence-defined recombinant antibodies (rAbs) have emerged as alternate choices to hybridoma-secreted monoclonal antibodies (mAbs) for performing immunoassays. However, the polyploidy nature of hybridomas normally ends in the coexistence of aberrant or non-specific sensible variable space (VR) gene transcripts, which complicates the identification of proper VR sequences.
  • Herein, we launched utilizing LC-MS/MS combined with next-generation sequencing to characterize VR sequences in an anti-thiaclopridmAb, which was produced by a hybridoma with genetic antibody selection.
  • The understanding of VR sequences was verified by the sensible analysis based totally on the recombinant antibody (rAb) expressed by HEK293 mammalian cells. The effectivity of the rAb was very like that of the parental mAb, with IC50 values of 0.73 and 0.46 μg/L as measured by ELISAs.
  • Moreover, molecular docking analysis revealed that Ser52 (H-CDR2), Trp98, and Trp93 (L-CDR3) residues inside the complementarity determining areas (CDRs) of the acknowledged VR sequences predominantly contributed to thiacloprid-specific recognition by way of hydrogen bonds and the CH-π interaction.
  • By way of single-site-directed alanine mutagenesis, we found that Trp98 and Trp93 (L-CDR3) confirmed extreme affinity to thiacloprid, whereas Ser52 (H-CDR2) had an auxiliary influence on the actual binding. This analysis presents an surroundings pleasant and reliable strategy to determine the vital factor recognition web sites of hapten-specific mAbs, facilitating the event of antibody properties.

 

RNAemia Corresponds to Sickness Severity and Antibody Response in Hospitalized COVID-19 Victims

Excessive acute respiratory syndrome coronavirus 2 (SARS-CoV-2) represents a worldwide effectively being emergency. To boost the understanding of the systemic aspect of SARS-CoV-2, we investigated if viral load dynamics in plasma and respiratory samples are associated to antibody response and severity of coronavirus sickness 2019 (COVID-19). SARS-CoV-2 RNA was current in plasma samples from 14 (44%) out of 32 victims.

RNAemia was detected in 5 out of 6 lethal cases. Peak IgG values have been significantly lower in delicate/affordable than in excessive (0.6 (interquartile fluctuate, IQR, 0.4-3.2) vs. 11.8 (IQR, 9.9-13.0), adjusted p = 0.003) or important cases (11.29 (IQR, 8.3-12.0), adjusted p = 0.042).

IgG titers have been significantly associated to virus Ct (Cycle threshold) value in plasma and respiratory specimens ((ß = 0.4, 95% CI (confidence interval, 0.2; 0.5), p< 0.001 and ß = 0.5, 95% CI (0.2; 0.6), p = 0.002).

A classification as excessive or a important case was furthermore inversely associated to Ct values in plasma in comparison with delicate/affordable cases (ß = -3.3, 95% CI (-5.8; 0.8), p = 0.024 and ß = -4.4, 95% CI (-7.2; 1.6), p = 0.007, respectively). Based on the present information, our hypothesis is that the early stage of SARS-CoV-2 an an infection is characterised by a most important RNAemia, as a potential manifestation of a systemic an an infection. Furthermore, the viral load in plasma seems to be associated to a worse sickness consequence.

Fc-binding antibody-recruiting molecules exploit endogenous antibodies for anti-tumor immune responses

 

Redirecting endogenous antibodies in the bloodstream to tumor cells using synthetic molecules is a promising approach to trigger anti-tumor immune responses. However, current molecular designs only enable the use of a small fraction of endogenous antibodies, limiting the therapeutic potential. Here, we report Fc-binding antibody-recruiting molecules (Fc-ARMs) as the first example addressing this issue. Fc-ARMs are composed of an Fc-binding peptide and a targeting ligand, enabling the exploitation of endogenous antibodies through constant affinity to the Fc region of antibodies, whose sequence is conserved in contrast to the Fab region.

We show that Fc-ARM targeting folate receptor-α (FR-α) redirects a clinically used antibody mixture to FR-α+ cancer cells, resulting in cancer cell lysis by natural killer cells in vitro. Fc-ARMs successfully interacted with antibodies in vivo and accumulated in tumors. Furthermore, Fc-ARMs recruited antibodies to suppress tumor growth in a mouse model. Thus, Fc-ARMs have the potential to be a novel class of cancer immunotherapeutic agents.

Significance of hepatitis B surface antigen, IgM/IgG core antibody and hepatitis B virus DNA in blood donors

 

Introduction: Identification of hepatitis B virus carriers in blood donors is imperative in order to avoid transmission of the disease via blood transfusion.

Objective: To determine if blood donors with positive results for serological markers HBsAg and anti-HBc were hepatitis B virus DNA carriers.

Methods: 12,745 samples were collected from six Ecuadorian blood banks and analyzed for HBsAg, anti-HBc and anti-HBs infectious markers by automated ELISA. All samples that tested positive for one, two or all three markers were analyzed with molecular techniques to determine the presence of viral DNA.

Results: 27.5 % of the samples that were reactive for anti-HBc alone and 100 % of those with positive results for HbsAg and IgM/IgG anti-HBc were identified to contain hepatitis B virus DNA (p = 0.001).

Conclusions: The selection of infection markers, as well as the detection methods define the results. Performing two serological and one molecular test is important in order to identify hepatitis B virus carriers and prevent its transmission.

Introducción: La identificación de portadores del virus de la hepatitis B en donantes de sangre es imperativo para evitar la transmisión de la enfermedad a través de transfusiones sanguíneas.

Objetivo: Determinar si los donantes de sangre con resultados positivos en los marcadores serológicos HbsAg y anti-HBc eran portadores del ADN del virus de la hepatitis B.

Métodos: Se recolectaron 12 745 muestras de seis bancos de sangre ecuatorianos, las cuales fueron analizadas con pruebas serológicas para identificar marcadores infecciosos de HBsAg, anti-HBc, anti-HBs mediante ELISA automatizada. Todas las muestras positivas para uno, dos o los tres marcadores fueron analizadas con técnica molecular para determinar la presencia del ADN viral.

Mouse Calcitonin (CT) ELISA Kit
RDR-CT-Mu-48Tests 48 Tests
EUR 511
Mouse Calcitonin (CT) ELISA Kit
RDR-CT-Mu-96Tests 96 Tests
EUR 709
Mouse Calcitonin (CT) ELISA Kit
RD-CT-Mu-48Tests 48 Tests
EUR 489
Mouse Calcitonin (CT) ELISA Kit
RD-CT-Mu-96Tests 96 Tests
EUR 677
Canine Calcitonin (CT) ELISA Kit
DLR-CT-c-48T 48T
EUR 527
  • Should the Canine Calcitonin (CT) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Canine Calcitonin (CT) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Canine Calcitonin (CT) ELISA Kit
DLR-CT-c-96T 96T
EUR 688
  • Should the Canine Calcitonin (CT) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A sandwich quantitative ELISA assay kit for detection of Canine Calcitonin (CT) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Human Calcitonin (CT) ELISA Kit
DLR-CT-Hu-48T 48T
EUR 441
  • Should the Human Calcitonin (CT) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A competitive inhibition quantitative ELISA assay kit for detection of Human Calcitonin (CT) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Human Calcitonin (CT) ELISA Kit
DLR-CT-Hu-96T 96T
EUR 570
  • Should the Human Calcitonin (CT) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A competitive inhibition quantitative ELISA assay kit for detection of Human Calcitonin (CT) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Rat Calcitonin (CT) ELISA Kit
DLR-CT-Ra-48T 48T
EUR 508
  • Should the Rat Calcitonin (CT) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A competitive inhibition quantitative ELISA assay kit for detection of Rat Calcitonin (CT) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Rat Calcitonin (CT) ELISA Kit
DLR-CT-Ra-96T 96T
EUR 661
  • Should the Rat Calcitonin (CT) ELISA Kit is proven to show malperformance, you will receive a refund or a free replacement.
Description: A competitive inhibition quantitative ELISA assay kit for detection of Rat Calcitonin (CT) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates or other biological fluids.
Canine Calcitonin (CT) ELISA Kit
RDR-CT-c-48Tests 48 Tests
EUR 557
Canine Calcitonin (CT) ELISA Kit
RDR-CT-c-96Tests 96 Tests
EUR 774
Human Calcitonin (CT) ELISA Kit
RDR-CT-Hu-48Tests 48 Tests
EUR 455
Human Calcitonin (CT) ELISA Kit
RDR-CT-Hu-96Tests 96 Tests
EUR 629
Rat Calcitonin (CT) ELISA Kit
RDR-CT-Ra-48Tests 48 Tests
EUR 534
Rat Calcitonin (CT) ELISA Kit
RDR-CT-Ra-96Tests 96 Tests
EUR 742
Canine Calcitonin (CT) ELISA Kit
RD-CT-c-48Tests 48 Tests
EUR 533
Canine Calcitonin (CT) ELISA Kit
RD-CT-c-96Tests 96 Tests
EUR 740
Human Calcitonin (CT) ELISA Kit
RD-CT-Hu-48Tests 48 Tests
EUR 436
Human Calcitonin (CT) ELISA Kit
RD-CT-Hu-96Tests 96 Tests
EUR 601
Rat Calcitonin (CT) ELISA Kit
RD-CT-Ra-48Tests 48 Tests
EUR 511
Rat Calcitonin (CT) ELISA Kit
RD-CT-Ra-96Tests 96 Tests
EUR 709
monoclonal anti-Human Calcitonin (CT) IgG
CT12-M 100 ug
EUR 482
Calcitonin (CT) Monoclonal Antibody (Human)
4-MAA472Hu22
  • EUR 265.00
  • EUR 2800.00
  • EUR 691.00
  • EUR 336.00
  • EUR 221.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Ala25~Cys85
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Mouse monoclonal antibody against Human Calcitonin (CT)
Calcitonin (CT) Monoclonal Antibody (Rat)
4-MAA472Ra21
  • EUR 251.00
  • EUR 2589.00
  • EUR 643.00
  • EUR 317.00
  • EUR 216.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Inquire for antigen sequence.
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Mouse monoclonal antibody against Rat Calcitonin (CT)
monoclonal anti-Human Calcitonin (CT) IgG #2
CT13-M 100 ug
EUR 482
Calcitonin (CT) Monoclonal Antibody (Human), APC
4-MAA472Hu22-APC
  • EUR 373.00
  • EUR 3671.00
  • EUR 1011.00
  • EUR 479.00
  • EUR 231.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Ala25~Cys85
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Mouse monoclonal antibody against Human Calcitonin (CT). This antibody is labeled with APC.
Calcitonin (CT) Monoclonal Antibody (Human), Biotinylated
4-MAA472Hu22-Biotin
  • EUR 332.00
  • EUR 2750.00
  • EUR 800.00
  • EUR 410.00
  • EUR 227.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Ala25~Cys85
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Mouse monoclonal antibody against Human Calcitonin (CT). This antibody is labeled with Biotin.
Calcitonin (CT) Monoclonal Antibody (Human), Cy3
4-MAA472Hu22-Cy3
  • EUR 456.00
  • EUR 4853.00
  • EUR 1307.00
  • EUR 597.00
  • EUR 266.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Ala25~Cys85
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Mouse monoclonal antibody against Human Calcitonin (CT). This antibody is labeled with Cy3.
Calcitonin (CT) Monoclonal Antibody (Human), FITC
4-MAA472Hu22-FITC
  • EUR 318.00
  • EUR 2956.00
  • EUR 829.00
  • EUR 403.00
  • EUR 204.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Ala25~Cys85
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Mouse monoclonal antibody against Human Calcitonin (CT). This antibody is labeled with FITC.
Calcitonin (CT) Monoclonal Antibody (Human), HRP
4-MAA472Hu22-HRP
  • EUR 340.00
  • EUR 3198.00
  • EUR 893.00
  • EUR 432.00
  • EUR 217.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Ala25~Cys85
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Mouse monoclonal antibody against Human Calcitonin (CT). This antibody is labeled with HRP.
Calcitonin (CT) Monoclonal Antibody (Human), PE
4-MAA472Hu22-PE
  • EUR 318.00
  • EUR 2956.00
  • EUR 829.00
  • EUR 403.00
  • EUR 204.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Ala25~Cys85
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Mouse monoclonal antibody against Human Calcitonin (CT). This antibody is labeled with PE.
Calcitonin (CT) Monoclonal Antibody (Rat), APC
4-MAA472Ra21-APC
  • EUR 352.00
  • EUR 3383.00
  • EUR 939.00
  • EUR 450.00
  • EUR 223.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Inquire for antigen sequence.
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Mouse monoclonal antibody against Rat Calcitonin (CT). This antibody is labeled with APC.
Calcitonin (CT) Monoclonal Antibody (Rat), Biotinylated
4-MAA472Ra21-Biotin
  • EUR 316.00
  • EUR 2539.00
  • EUR 747.00
  • EUR 388.00
  • EUR 221.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Inquire for antigen sequence.
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Mouse monoclonal antibody against Rat Calcitonin (CT). This antibody is labeled with Biotin.
Calcitonin (CT) Monoclonal Antibody (Rat), Cy3
4-MAA472Ra21-Cy3
  • EUR 428.00
  • EUR 4469.00
  • EUR 1211.00
  • EUR 559.00
  • EUR 255.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Inquire for antigen sequence.
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Mouse monoclonal antibody against Rat Calcitonin (CT). This antibody is labeled with Cy3.
Calcitonin (CT) Monoclonal Antibody (Rat), FITC
4-MAA472Ra21-FITC
  • EUR 302.00
  • EUR 2726.00
  • EUR 771.00
  • EUR 380.00
  • EUR 198.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Inquire for antigen sequence.
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Mouse monoclonal antibody against Rat Calcitonin (CT). This antibody is labeled with FITC.
Calcitonin (CT) Monoclonal Antibody (Rat), HRP
4-MAA472Ra21-HRP
  • EUR 322.00
  • EUR 2948.00
  • EUR 830.00
  • EUR 407.00
  • EUR 210.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Inquire for antigen sequence.
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Mouse monoclonal antibody against Rat Calcitonin (CT). This antibody is labeled with HRP.
Calcitonin (CT) Monoclonal Antibody (Rat), PE
4-MAA472Ra21-PE
  • EUR 302.00
  • EUR 2726.00
  • EUR 771.00
  • EUR 380.00
  • EUR 198.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Inquire for antigen sequence.
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Mouse monoclonal antibody against Rat Calcitonin (CT). This antibody is labeled with PE.
Calcitonin (CT) Antibody
20-abx175651
  • EUR 1135.00
  • EUR 551.00
  • 1 mg
  • 200 ug
  • Please enquire.
Calcitonin (CT) Antibody
20-abx100227
  • EUR 425.00
  • EUR 133.00
  • EUR 1177.00
  • EUR 578.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-12 working days.
Calcitonin (CT) Antibody
20-abx100228
  • EUR 411.00
  • EUR 133.00
  • EUR 1135.00
  • EUR 551.00
  • EUR 314.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.
Calcitonin (CT) Antibody
20-abx100230
  • EUR 1177.00
  • EUR 578.00
  • 1 mg
  • 200 ug
  • Please enquire.
Calcitonin (CT) Antibody
20-abx104916
  • EUR 439.00
  • EUR 133.00
  • EUR 1233.00
  • EUR 592.00
  • EUR 328.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.
Calcitonin (CT) Antibody
20-abx171510
  • EUR 871.00
  • EUR 453.00
  • 1 mg
  • 200 ug
  • Please enquire.
Calcitonin (CT) Polyclonal Antibody (Mouse)
4-PAA472Mu01
  • EUR 236.00
  • EUR 2338.00
  • EUR 586.00
  • EUR 294.00
  • EUR 209.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Val26~Asn136
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Calcitonin (CT)
Mouse Calcitonin (CT) Protein
20-abx065656
  • EUR 592.00
  • EUR 258.00
  • EUR 1776.00
  • EUR 704.00
  • EUR 439.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.
Calcitonin (CT) Monoclonal Antibody (Human), APC-Cy7
4-MAA472Hu22-APC-Cy7
  • EUR 626.00
  • EUR 7222.00
  • EUR 1903.00
  • EUR 839.00
  • EUR 342.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Ala25~Cys85
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Mouse monoclonal antibody against Human Calcitonin (CT). This antibody is labeled with APC-Cy7.
Calcitonin (CT) Monoclonal Antibody (Rat), APC-Cy7
4-MAA472Ra21-APC-Cy7
  • EUR 585.00
  • EUR 6646.00
  • EUR 1759.00
  • EUR 781.00
  • EUR 326.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Inquire for antigen sequence.
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Mouse monoclonal antibody against Rat Calcitonin (CT). This antibody is labeled with APC-Cy7.
Calcitonin (CT) Antibody (Biotin)
20-abx271724
  • EUR 481.00
  • EUR 244.00
  • EUR 1414.00
  • EUR 662.00
  • EUR 356.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-15 working days.
Calcitonin (CT) Antibody (Biotin)
20-abx271988
  • EUR 439.00
  • EUR 244.00
  • EUR 1274.00
  • EUR 606.00
  • EUR 342.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.
Recombinant Calcitonin (CT)
4-RPA472Ca01
  • EUR 503.20
  • EUR 238.00
  • EUR 1612.00
  • EUR 604.00
  • EUR 1108.00
  • EUR 400.00
  • EUR 3880.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: P41547
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 15.1kDa
  • Isoelectric Point: Inquire
Description: Recombinant Dog Calcitonin expressed in: E.coli
Recombinant Calcitonin (CT)
4-RPA472Hu01
  • EUR 384.93
  • EUR 206.00
  • EUR 1168.48
  • EUR 456.16
  • EUR 812.32
  • EUR 320.00
  • EUR 2771.20
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: P01258
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 36.6kDa
  • Isoelectric Point: 5.7
Description: Recombinant Human Calcitonin expressed in: E.coli
Recombinant Calcitonin (CT)
4-RPA472Mu01
  • EUR 422.56
  • EUR 216.00
  • EUR 1309.60
  • EUR 503.20
  • EUR 906.40
  • EUR 346.00
  • EUR 3124.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: P70160
  • Buffer composition: PBS, pH 7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): 14.7kDa
  • Isoelectric Point: Inquire
Description: Recombinant Mouse Calcitonin expressed in: E.coli
Calcitonin (CT) Polyclonal Antibody (Mouse), APC
4-PAA472Mu01-APC
  • EUR 329.00
  • EUR 3041.00
  • EUR 854.00
  • EUR 416.00
  • EUR 212.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Val26~Asn136
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Calcitonin (CT). This antibody is labeled with APC.
Calcitonin (CT) Polyclonal Antibody (Mouse), Biotinylated
4-PAA472Mu01-Biotin
  • EUR 299.00
  • EUR 2288.00
  • EUR 684.00
  • EUR 363.00
  • EUR 214.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Val26~Asn136
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Calcitonin (CT). This antibody is labeled with Biotin.
Calcitonin (CT) Polyclonal Antibody (Mouse), Cy3
4-PAA472Mu01-Cy3
  • EUR 397.00
  • EUR 4013.00
  • EUR 1097.00
  • EUR 513.00
  • EUR 241.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Val26~Asn136
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Calcitonin (CT). This antibody is labeled with Cy3.
Calcitonin (CT) Polyclonal Antibody (Mouse), FITC
4-PAA472Mu01-FITC
  • EUR 283.00
  • EUR 2452.00
  • EUR 703.00
  • EUR 353.00
  • EUR 189.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Val26~Asn136
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Calcitonin (CT). This antibody is labeled with FITC.
Calcitonin (CT) Polyclonal Antibody (Mouse), HRP
4-PAA472Mu01-HRP
  • EUR 302.00
  • EUR 2652.00
  • EUR 756.00
  • EUR 377.00
  • EUR 200.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Val26~Asn136
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Calcitonin (CT). This antibody is labeled with HRP.
Calcitonin (CT) Polyclonal Antibody (Mouse), PE
4-PAA472Mu01-PE
  • EUR 283.00
  • EUR 2452.00
  • EUR 703.00
  • EUR 353.00
  • EUR 189.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Val26~Asn136
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Calcitonin (CT). This antibody is labeled with PE.
Mouse Calcitonin, CT ELISA Kit
CSB-E05133m-24T 1 plate of 24 wells
EUR 165
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Mouse Calcitonin, CT in samples from serum, plasma, cell culture supernates, tissue homogenates. A new trial version of the kit, which allows you to test the kit in your application at a reasonable price.
Mouse Calcitonin, CT ELISA Kit
1-CSB-E05133m
  • EUR 967.00
  • EUR 5925.00
  • EUR 3134.00
  • 1 plate of 96 wells
  • 10 plates of 96 wells each
  • 5 plates of 96 wells each
  • Sample volume: 50-100ul
  • Detection wavelength: 450nm
  • Assay performance time: 1 to 4 hours.
Description: Quantitativesandwich ELISA kit for measuring Mouse Calcitonin, CT in samples from serum, plasma, cell culture supernates, tissue homogenates. Now available in a cost efficient pack of 5 plates of 96 wells each, conveniently packed along with the other reagents in 5 separate kits.
Mouse Calcitonin (CT) CLIA Kit
abx196301-96tests 96 tests
EUR 825
  • Shipped within 5-12 working days.
Mouse Calcitonin (CT) ELISA Kit
CEA472Mu-10x96wellstestplate 10x96-wells test plate
EUR 4391.16
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Mouse Calcitonin (CT) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of Mouse Calcitonin (CT) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
Mouse Calcitonin (CT) ELISA Kit
CEA472Mu-1x48wellstestplate 1x48-wells test plate
EUR 449.27
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Mouse Calcitonin (CT) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of Mouse Calcitonin (CT) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
Mouse Calcitonin (CT) ELISA Kit
CEA472Mu-1x96wellstestplate 1x96-wells test plate
EUR 598.96
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Mouse Calcitonin (CT) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of Mouse Calcitonin (CT) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
Mouse Calcitonin (CT) ELISA Kit
CEA472Mu-5x96wellstestplate 5x96-wells test plate
EUR 2395.32
  • The Intra-assay Precision is determined when 3 samples with low, middle and high level of Mouse Calcitonin (CT) were tested on 3 different plates, 8 replicates in each plate
  • CV(%) = SD/meanX100
  • Intra-Assay: CV<10%
  • Inter-Assay: CV<12%
Description: This is Competitive Enzyme-linked immunosorbent assay for detection of Mouse Calcitonin (CT) in serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids.
Mouse Calcitonin (CT) ELISA Kit
4-CEA472Mu
  • EUR 4442.00
  • EUR 2346.00
  • EUR 599.00
  • 10 plates of 96 wells
  • 5 plates of 96 wells
  • 1 plate of 96 wells
  • Known also as Calcitonin elisa. Alternative names of the recognized antigen: CALCA
  • CALC1
  • CGRP-I
  • CGRP1
  • KC
  • CCP
  • PDN-21
  • Katacalcin
  • Calcitonin-Related Polypeptide Alpha
  • Calcitonin carboxyl-terminal peptide
Description: Enzyme-linked immunosorbent assay based on the Competitive Inhibition method for detection of Mouse Calcitonin (CT) in samples from serum, plasma, tissue homogenates, cell lysates, cell culture supernates and other biological fluids with no significant corss-reactivity with analogues from other species.
Mouse Calcitonin,CT ELISA Kit
CN-02845M1 96T
EUR 434
Mouse Calcitonin,CT ELISA Kit
CN-02845M2 48T
EUR 284
Mouse CT(Calcitonin) ELISA Kit
EM0954 96T
EUR 476.25
  • Detection range: 15.625-1000 pg/ml
  • Alias: CT/Calcitonin/Thyrocalcitonin
Description: Method of detection: Coated with Antigen, Competitive ELISA;Reacts with: Mus ;Sensitivity: 9.375pg/ml
Mouse Calcitonin(CT)ELISA Kit
GA-E0083MS-48T 48T
EUR 336
Mouse Calcitonin(CT)ELISA Kit
GA-E0083MS-96T 96T
EUR 534
Mouse Calcitonin ELISA Kit (CT)
RK02716 96 Tests
EUR 521
Mouse Calcitonin(CT)ELISA Kit
QY-E20233 96T
EUR 361
Calcitonin (CT) Polyclonal Antibody (Dog)
4-PAA472Ca01
  • EUR 251.00
  • EUR 2576.00
  • EUR 640.00
  • EUR 316.00
  • EUR 215.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: CT (Ala26~Arg130)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Dog Calcitonin (CT)
Calcitonin (CT) Polyclonal Antibody (Human)
4-PAA472Hu01
  • EUR 242.00
  • EUR 2444.00
  • EUR 610.00
  • EUR 304.00
  • EUR 212.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Inquire for antigen sequence.
  • Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Description: A Rabbit polyclonal antibody against Human Calcitonin (CT)
Calcitonin (CT) Polyclonal Antibody (Human)
4-PAA472Hu02
  • EUR 242.00
  • EUR 2444.00
  • EUR 610.00
  • EUR 304.00
  • EUR 212.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Inquire for antigen sequence.
  • Buffer composition: PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Description: A Rabbit polyclonal antibody against Human Calcitonin (CT)
Dog Calcitonin (CT) Protein
20-abx168025
  • EUR 704.00
  • EUR 286.00
  • EUR 2165.00
  • EUR 829.00
  • EUR 495.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.
Human Calcitonin (CT) Protein
20-abx065655
  • EUR 551.00
  • EUR 244.00
  • EUR 1581.00
  • EUR 634.00
  • EUR 398.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-7 working days.
Human Calcitonin (CT) Protein
20-abx652322
  • EUR 578.00
  • EUR 258.00
  • EUR 1720.00
  • EUR 690.00
  • EUR 425.00
  • 100 ug
  • 10 ug
  • 1 mg
  • 200 ug
  • 50 ug
  • Shipped within 5-15 working days.
BSA conjugated Calcitonin (CT)
4-CPA472Hu11
  • EUR 413.60
  • EUR 214.00
  • EUR 1276.00
  • EUR 492.00
  • EUR 884.00
  • EUR 340.00
  • EUR 3040.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: P01258
  • Buffer composition: PBS, pH 7.4.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): Inquire
  • Isoelectric Point: Inquire
Description: Recombinant Human Calcitonin expressed in: Protein conjugation
OVA conjugated Calcitonin (CT)
4-CPA472Hu21
  • EUR 413.60
  • EUR 214.00
  • EUR 1276.00
  • EUR 492.00
  • EUR 884.00
  • EUR 340.00
  • EUR 3040.00
  • 100 ug
  • 10ug
  • 1 mg
  • 200 ug
  • 500 ug
  • 50ug
  • 5 mg
  • Uniprot ID: P01258
  • Buffer composition: PBS, pH 7.4.
  • Form: Freeze-dried powder
  • Predicted Molecular Mass (KD): Inquire
  • Isoelectric Point: Inquire
Description: Recombinant Human Calcitonin expressed in: Protein conjugation
Mouse Anti Human Calcitonin Monoclonal Antibody
CABT-49104MH 0.2 mg
EUR 710
Calcitonin (CT) Polyclonal Antibody (Mouse), APC-Cy7
4-PAA472Mu01-APC-Cy7
  • EUR 538.00
  • EUR 5962.00
  • EUR 1588.00
  • EUR 713.00
  • EUR 304.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: Val26~Asn136
  • Buffer composition: 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol.
Description: A Rabbit polyclonal antibody against Mouse Calcitonin (CT). This antibody is labeled with APC-Cy7.
CLIA kit for Mouse CT (Calcitonin)
E-CL-M0158 1 plate of 96 wells
EUR 584
  • Gentaur's CT CLIA kit utilizes the Sandwich- CLIA principle. The micro CLIA plate provided in this kit has been pre-coated with an antibody specific to Mouse CT . Standards or samples are added to the micro CLIA plate wells and combined with the spec
  • Show more
Description: A sandwich CLIA kit for quantitative measurement of Mouse CT (Calcitonin) in samples from Serum, Plasma, Cell supernatant
ELISA kit for Mouse CT (Calcitonin)
E-EL-M0217 1 plate of 96 wells
EUR 377
  • Gentaur's CT ELISA kit utilizes the Sandwich-ELISA principle. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to Mouse CT. Standards or samples are added to the micro ELISA plate wells and combined with the sp
  • Show more
Description: A sandwich ELISA kit for quantitative measurement of Mouse CT (Calcitonin) in samples from Serum, Plasma, Cell supernatant
ELISA kit for Mouse CT (Calcitonin)
ELK2393 1 plate of 96 wells
EUR 432
  • A monoclonal antibody specific to Calcitonin (CT) has been pre-coated onto a microplate. A competitive inhibition reaction is launched between biotin labeled Calcitonin (CT) and unlabeled Calcitonin (CT) (Standards or samples) with the pre-coated ant
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Description: A competitive Inhibition ELISA kit for detection of Calcitonin from Mouse in samples from blood, serum, plasma, cell culture fluid and other biological fluids.
Calcitonin (CT) Polyclonal Antibody (Dog), APC
4-PAA472Ca01-APC
  • EUR 351.00
  • EUR 3365.00
  • EUR 935.00
  • EUR 449.00
  • EUR 222.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: CT (Ala26~Arg130)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Dog Calcitonin (CT). This antibody is labeled with APC.
Calcitonin (CT) Polyclonal Antibody (Dog), Biotinylated
4-PAA472Ca01-Biotin
  • EUR 316.00
  • EUR 2526.00
  • EUR 744.00
  • EUR 387.00
  • EUR 221.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: CT (Ala26~Arg130)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Dog Calcitonin (CT). This antibody is labeled with Biotin.
Calcitonin (CT) Polyclonal Antibody (Dog), Cy3
4-PAA472Ca01-Cy3
  • EUR 427.00
  • EUR 4445.00
  • EUR 1205.00
  • EUR 557.00
  • EUR 254.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: CT (Ala26~Arg130)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Dog Calcitonin (CT). This antibody is labeled with Cy3.
Calcitonin (CT) Polyclonal Antibody (Dog), FITC
4-PAA472Ca01-FITC
  • EUR 301.00
  • EUR 2712.00
  • EUR 768.00
  • EUR 379.00
  • EUR 197.00
  • 100ul
  • 10ml
  • 1ml
  • 200ul
  • 20ul
  • Sequence of the immunogen: CT (Ala26~Arg130)
  • Buffer composition: PBS, pH7.4, containing 0.02% NaN3, 50% glycerol.
Description: A Rabbit polyclonal antibody against Dog Calcitonin (CT). This antibody is labeled with FITC.

 

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